Experiments with mice and with human cells have found that lean fat cells in the breast produce an oxylpin molecule (9S-HODE) that strongly suppresses the growth of cancer cells by inducing ferroptosis. Obesity reduces the secretion of 9S-HODE, and thus its protective effect. In humans, 9S-HODE in breast tissue is inversely correlated with BMI. Summary: https://scitechdaily.com/obesity-could-disable-a-key-defense-against-breast-cancer-study-finds/ Original paper: https://www.science.org/doi/10.1126/science.aea4287 #Science #Health #WomensHealth #BreastCancer #Cancer #Obesity #BMI