A six-week RCT evaluated the effect on knee osteoarthritis of inulin (prebiotic) supplementation, physical therapy (PT), both, or a placebo in 117 adults. Inulin and PT both reduced pain. Inulin also reduced pain sensitivity generally. Action is presumed to be through the gut microbiome, butyrate, and reduced inflammation. Compliance with supplementation was much better than with PT. Summary: https://www.sciencedaily.com/releases/2026/10/261027230715.htm Paper: https://www.mdpi.com/2072-6643/18/5/714 #Science #Health #Arthritis #Prebiotics