there’s no problem with getting nitrogen or argon, maybe they need it for their biological things specifically -80 freezers will be necessary in the future but some new refrigerant will be needed for them, there’s no way R23 or R116 will be approved forever (gwp 10k+). i guess that will have to be ethane/ethylene + propane cascade? if so that would be blast from the past because ethylene was used as an intermediate refrigerant in first oxygen liquefaction