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@jeneralist@mstdn.science

2026-07-18 13:09 UTC

@ducky@mstdn.ca @DavidPenington@aus.social The catch is, right now we don't know how EBV does all those things. If the problems come not from the virus, but from the immune system's response to the virus, making a vaccine gets extra tricky.

Replies (1)

  • @ducky@mstdn.ca 2026-07-18 19:12

    @jeneralist@mstdn.science @DavidPenington@aus.social I agree that if it's the immune system response to EBV which attack the body (e.g. the myelin in MS), then a vaccine would be a bad idea. However, the paper which I reference in the head post of this thread says that people with MS have elevated levels of CD4+ targeting late lytic capsid and glycoprotein antigens, while non-MS people have more CD8 targeting a nuclear antigen. I am not a doctor or microbiologist, but this makes me think that a vax with EBV nuclear antigens but not lytic capsid and glycoprotein antigens in it might stop the EBV without any danger of MS. I see the MD/PhD in your handle, please correct me if I am wrong! And for ME/CFS and Long COVID, the papers (well, abstracts) which I read talk about how they see evidence of EBV reactivation in those, which doesn't sound to me (not a doctor! not a microbiologist!) like an autoimmune dysfunction.

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